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Molecular Epidemiology of Blastomyces gilchristii Clusters, Minnesota, USA

We characterized 2 clusters of blastomycosis cases in Minnesota, USA, using whole-genome sequencing and single-nucleotide polymorphism analyses. Blastomyces gilchristii was confirmed as the cause of infection. Genomic analyses corresponded with epidemiologic findings for cases of B. gilchristii infe...

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Detalles Bibliográficos
Autores principales: Bagal, Ujwal R., Ireland, Malia, Gross, Annastasia, Fischer, Jill, Bentz, Meghan, Berkow, Elizabeth L., Litvintseva, Anastasia P., Chow, Nancy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423935/
https://www.ncbi.nlm.nih.gov/pubmed/35997504
http://dx.doi.org/10.3201/eid2809.220392
Descripción
Sumario:We characterized 2 clusters of blastomycosis cases in Minnesota, USA, using whole-genome sequencing and single-nucleotide polymorphism analyses. Blastomyces gilchristii was confirmed as the cause of infection. Genomic analyses corresponded with epidemiologic findings for cases of B. gilchristii infections, demonstrating the utility of genomic methods for future blastomycosis outbreak investigations.