Cargando…

KLHL14: A Novel Prognostic Biomarker and Therapeutic Target for Ovarian Cancer

Ovarian cancer (OV) is a gynaecological malignancy that poses a serious risk to the health status of women. To date, effective molecular markers are unavailable for the diagnosis and management of ovarian malignancies. In this study, we aimed to investigate the molecular markers associated with the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xingwei, Sun, Ru, Hong, Xia, Chen, Chen, Ding, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423958/ https://www.ncbi.nlm.nih.gov/pubmed/36046368 http://dx.doi.org/10.1155/2022/9799346

Ejemplares similares

KLHL5 Is a Prognostic-Related Biomarker and Correlated With Immune Infiltrates in Gastric Cancer
por: Wu, Qiulin, et al.
Publicado: (2020)

Tissue- and Cell Type-Specific Expression of the Long Noncoding RNA Klhl14-AS in Mouse
por: Credendino, Sara Carmela, et al.
Publicado: (2017)

A synthetic KLHL20 ligand to validate CUL3(KLHL20) as a potent E3 ligase for targeted protein degradation
por: Farrell, Brian M., et al.
Publicado: (2022)

Clinical Outcome in KLHL24 Cardiomyopathy
por: Vermeer, Mathilde C.S.C., et al.
Publicado: (2023)

MRPL15 is a novel prognostic biomarker and therapeutic target for epithelial ovarian cancer
por: Xu, Haoya, et al.
Publicado: (2021)

Transcriptomic and computational analysis identified LPA metabolism, KLHL14 and KCNE3 as novel regulators of Epithelial-Mesenchymal Transition
por: Di Lollo, V., et al.
Publicado: (2020)

KLHL21, a novel gene that contributes to the progression of hepatocellular carcinoma
por: Shi, Lei, et al.
Publicado: (2016)

The I510V mutation in KLHL10 in a patient with oligoasthenoteratozoospermia
por: HUANG, Zicong, et al.
Publicado: (2021)

Overexpression of KLHL23 protein from read‐through transcription of PHOSPHO2‐KLHL23 in gastric cancer increases cell proliferation
por: Choi, Eun‐Seok, et al.
Publicado: (2016)

Update on the Kelch-like (KLHL) gene family
por: Dhanoa, Bajinder S, et al.
Publicado: (2013)

Immune-Related Genes’ Prognostic, Therapeutic and Diagnostic Value in Ovarian Cancer Immune-Related Gene Biomarker in Ovarian Cancer
por: Ding, Bo, et al.
Publicado: (2023)

KLHL41 stabilizes skeletal muscle sarcomeres by nonproteolytic ubiquitination
por: Ramirez-Martinez, Andres, et al.
Publicado: (2017)

X-linked intellectual disability related to a novel variant of KLHL15
por: Kido, Jun, et al.
Publicado: (2023)

Long Noncoding RNA PVT1 as a Novel Diagnostic Biomarker and Therapeutic Target for Melanoma
por: Chen, Xiangjun, et al.
Publicado: (2017)

Crystal Structure of KLHL3 in Complex with Cullin3
por: Ji, Alan X., et al.
Publicado: (2013)

Cardiomyopathy with lethal arrhythmias associated with inactivation of KLHL24
por: Hedberg-Oldfors, Carola, et al.
Publicado: (2019)

Role of Syndecans in Ovarian Cancer: New Diagnostic and Prognostic Biomarkers and Potential Therapeutic Targets
por: Oto, Julia, et al.
Publicado: (2023)

KLHL5 knockdown increases cellular sensitivity to anticancer drugs
por: Schleifer, Robert J., et al.
Publicado: (2018)

Epigenetics of Muscle- and Brain-Specific Expression of KLHL Family Genes
por: Ehrlich, Kenneth C., et al.
Publicado: (2020)

Cyclin genes as potential novel prognostic biomarkers and therapeutic targets in breast cancer
por: Liu, Nian-Qiu, et al.
Publicado: (2022)

Circular RNAs in Epithelial Ovarian Cancer: From Biomarkers to Therapeutic Targets
por: Qiu, Yumin, et al.
Publicado: (2022)

Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase
por: Chen, Zhuoyao, et al.
Publicado: (2019)

HCK can serve as novel prognostic biomarker and therapeutic target for Breast Cancer patients
por: Zhu, Xudong, et al.
Publicado: (2020)

KLHL7 promotes hepatocellular carcinoma progression and molecular therapy resistance by degrading RASA2
por: Chen, Lin, et al.
Publicado: (2023)

New macular findings in individuals with biallelic KLHL7 gene mutation
por: Heng, Ling Zhi, et al.
Publicado: (2019)

Cul3-KLHL20 ubiquitin ligase: physiological functions, stress responses, and disease implications
por: Chen, Hsin-Yi, et al.
Publicado: (2016)

Novel KLHL26 variant associated with a familial case of Ebstein’s anomaly and left ventricular noncompaction
por: Samudrala, Sai Suma K., et al.
Publicado: (2020)

PDK4 Constitutes a Novel Prognostic Biomarker and Therapeutic Target in Gastric Cancer
por: Zhang, Zimu, et al.
Publicado: (2022)

EGFR as a prognostic biomarker and therapeutic target in ovarian cancer: evaluation of patient cohort and literature review
por: Mehner, Christine, et al.
Publicado: (2017)

Identification of novel therapeutic target and prognostic biomarker in matrix metalloproteinase gene family in pancreatic cancer
por: Luan, Hong, et al.
Publicado: (2023)

Novel mutations in the 3-box motif of the BACK domain of KLHL7 associated with nonsyndromic autosomal dominant retinitis pigmentosa
por: Oh, Jin Kyun, et al.
Publicado: (2019)

Cullin3–KLHL25 ubiquitin ligase targets ACLY for degradation to inhibit lipid synthesis and tumor progression
por: Zhang, Cen, et al.
Publicado: (2016)

Regulating PLK1 dynamics by Cullin3/KLHL22-mediated ubiquitylation
por: Beck, Jochen, et al.
Publicado: (2013)

Cardiac transplant for epidermolysis bullosa simplex with KLHL24 mutation–associated cardiomyopathy
por: Grilletta, Erica Ann
Publicado: (2019)

Role of KLHL3 and dietary K(+) in regulating KS-WNK1 expression
por: Ostrosky-Frid, Mauricio, et al.
Publicado: (2021)

Identification of PSMD14 as a potential novel prognosis biomarker and therapeutic target for osteosarcoma
por: Gong, Yubao, et al.
Publicado: (2021)

Identification and validation of novel prognostic biomarkers and therapeutic targets for non-small cell lung cancer
por: Lai, Li-Ting, et al.
Publicado: (2023)

CEACAM6 is a prognostic biomarker and potential therapeutic target for gastric carcinoma
por: Ru, Guo-Qing, et al.
Publicado: (2017)

A novel and recurrent KLHL40 pathogenic variants in a Chinese family of multiple affected neonates with nemaline myopathy 8
por: Yi, Sheng, et al.
Publicado: (2021)

Determination of Potential Therapeutic Targets and Prognostic Markers of Ovarian Cancer by Bioinformatics Analysis
por: Zhang, Jing, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_81mbtn5cvgipnu46fk8h9hqpdh