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Methylation and copy number profiling: emerging tools to differentiate osteoblastoma from malignant mimics?
Rearrangements of the transcription factors FOS and FOSB have recently been identified as the genetic driver event underlying osteoid osteoma and osteoblastoma. Nuclear overexpression of FOS and FOSB have since then emerged as a reliable surrogate marker despite limitations in specificity and sensit...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424109/ https://www.ncbi.nlm.nih.gov/pubmed/35347251 http://dx.doi.org/10.1038/s41379-022-01071-1 |