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Methylation and copy number profiling: emerging tools to differentiate osteoblastoma from malignant mimics?

Rearrangements of the transcription factors FOS and FOSB have recently been identified as the genetic driver event underlying osteoid osteoma and osteoblastoma. Nuclear overexpression of FOS and FOSB have since then emerged as a reliable surrogate marker despite limitations in specificity and sensit...

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Detalles Bibliográficos
Autores principales: Ameline, Baptiste, Nathrath, Michaela, Nord, Karolin H., de Flon, Felix Haglund, Bovée, Judith V. M. G., Krieg, Andreas H., Höller, Sylvia, Hench, Jürgen, Baumhoer, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424109/
https://www.ncbi.nlm.nih.gov/pubmed/35347251
http://dx.doi.org/10.1038/s41379-022-01071-1