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Self-shrinking soft demoulding for complex high-aspect-ratio microchannels

Microchannels are the essential elements in animals, plants, and various artificial devices such as soft robotics, wearable sensors, and organs-on-a-chip. However, three-dimensional (3D) microchannels with complex geometry and a high aspect ratio remain challenging to generate by conventional method...

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Detalles Bibliográficos
Autores principales: Fan, Dongliang, Yuan, Xi, Wu, Wenyu, Zhu, Renjie, Yang, Xin, Liao, Yuxuan, Ma, Yunteng, Xiao, Chufan, Chen, Cheng, Liu, Changyue, Wang, Hongqiang, Qin, Peiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424246/
https://www.ncbi.nlm.nih.gov/pubmed/36038593
http://dx.doi.org/10.1038/s41467-022-32859-z
Descripción
Sumario:Microchannels are the essential elements in animals, plants, and various artificial devices such as soft robotics, wearable sensors, and organs-on-a-chip. However, three-dimensional (3D) microchannels with complex geometry and a high aspect ratio remain challenging to generate by conventional methods such as soft lithography, template dissolution, and matrix swollen processes, although they are widespread in nature. Here, we propose a simple and solvent-free fabrication method capable of producing monolithic microchannels with complex 3D structures, long length, and small diameter. A soft template and a peeling-dominant template removal process are introduced to the demoulding process, which is referred to as soft demoulding here. In combination with thermal drawing technology, microchannels with a small diameter (10 µm), a high aspect ratio (6000, length-to-diameter), and intricate 3D geometries are generated. We demonstrate the vast applicability and significant impact of this technology in multiple scenarios, including soft robotics, wearable sensors, soft antennas, and artificial vessels.