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Self-shrinking soft demoulding for complex high-aspect-ratio microchannels
Microchannels are the essential elements in animals, plants, and various artificial devices such as soft robotics, wearable sensors, and organs-on-a-chip. However, three-dimensional (3D) microchannels with complex geometry and a high aspect ratio remain challenging to generate by conventional method...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424246/ https://www.ncbi.nlm.nih.gov/pubmed/36038593 http://dx.doi.org/10.1038/s41467-022-32859-z |
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author | Fan, Dongliang Yuan, Xi Wu, Wenyu Zhu, Renjie Yang, Xin Liao, Yuxuan Ma, Yunteng Xiao, Chufan Chen, Cheng Liu, Changyue Wang, Hongqiang Qin, Peiwu |
author_facet | Fan, Dongliang Yuan, Xi Wu, Wenyu Zhu, Renjie Yang, Xin Liao, Yuxuan Ma, Yunteng Xiao, Chufan Chen, Cheng Liu, Changyue Wang, Hongqiang Qin, Peiwu |
author_sort | Fan, Dongliang |
collection | PubMed |
description | Microchannels are the essential elements in animals, plants, and various artificial devices such as soft robotics, wearable sensors, and organs-on-a-chip. However, three-dimensional (3D) microchannels with complex geometry and a high aspect ratio remain challenging to generate by conventional methods such as soft lithography, template dissolution, and matrix swollen processes, although they are widespread in nature. Here, we propose a simple and solvent-free fabrication method capable of producing monolithic microchannels with complex 3D structures, long length, and small diameter. A soft template and a peeling-dominant template removal process are introduced to the demoulding process, which is referred to as soft demoulding here. In combination with thermal drawing technology, microchannels with a small diameter (10 µm), a high aspect ratio (6000, length-to-diameter), and intricate 3D geometries are generated. We demonstrate the vast applicability and significant impact of this technology in multiple scenarios, including soft robotics, wearable sensors, soft antennas, and artificial vessels. |
format | Online Article Text |
id | pubmed-9424246 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-94242462022-08-31 Self-shrinking soft demoulding for complex high-aspect-ratio microchannels Fan, Dongliang Yuan, Xi Wu, Wenyu Zhu, Renjie Yang, Xin Liao, Yuxuan Ma, Yunteng Xiao, Chufan Chen, Cheng Liu, Changyue Wang, Hongqiang Qin, Peiwu Nat Commun Article Microchannels are the essential elements in animals, plants, and various artificial devices such as soft robotics, wearable sensors, and organs-on-a-chip. However, three-dimensional (3D) microchannels with complex geometry and a high aspect ratio remain challenging to generate by conventional methods such as soft lithography, template dissolution, and matrix swollen processes, although they are widespread in nature. Here, we propose a simple and solvent-free fabrication method capable of producing monolithic microchannels with complex 3D structures, long length, and small diameter. A soft template and a peeling-dominant template removal process are introduced to the demoulding process, which is referred to as soft demoulding here. In combination with thermal drawing technology, microchannels with a small diameter (10 µm), a high aspect ratio (6000, length-to-diameter), and intricate 3D geometries are generated. We demonstrate the vast applicability and significant impact of this technology in multiple scenarios, including soft robotics, wearable sensors, soft antennas, and artificial vessels. Nature Publishing Group UK 2022-08-29 /pmc/articles/PMC9424246/ /pubmed/36038593 http://dx.doi.org/10.1038/s41467-022-32859-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Fan, Dongliang Yuan, Xi Wu, Wenyu Zhu, Renjie Yang, Xin Liao, Yuxuan Ma, Yunteng Xiao, Chufan Chen, Cheng Liu, Changyue Wang, Hongqiang Qin, Peiwu Self-shrinking soft demoulding for complex high-aspect-ratio microchannels |
title | Self-shrinking soft demoulding for complex high-aspect-ratio microchannels |
title_full | Self-shrinking soft demoulding for complex high-aspect-ratio microchannels |
title_fullStr | Self-shrinking soft demoulding for complex high-aspect-ratio microchannels |
title_full_unstemmed | Self-shrinking soft demoulding for complex high-aspect-ratio microchannels |
title_short | Self-shrinking soft demoulding for complex high-aspect-ratio microchannels |
title_sort | self-shrinking soft demoulding for complex high-aspect-ratio microchannels |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424246/ https://www.ncbi.nlm.nih.gov/pubmed/36038593 http://dx.doi.org/10.1038/s41467-022-32859-z |
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