Cargando…
Tumor-associated macrophage (TAM)-derived CCL22 induces FAK addiction in esophageal squamous cell carcinoma (ESCC)
Tumor cell dependence on activated oncogenes is considered a therapeutic target, but protumorigenic microenvironment-mediated cellular addiction to specific oncogenic signaling molecules remains to be further defined. Here, we showed that tumor-associated macrophages (TAMs) produced an abundance of...
Autores principales: | Chen, Jie, Zhao, Di, Zhang, Lingyuan, Zhang, Jing, Xiao, Yuanfan, Wu, Qingnan, Wang, Yan, Zhan, Qimin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424285/ https://www.ncbi.nlm.nih.gov/pubmed/35962191 http://dx.doi.org/10.1038/s41423-022-00903-z |
Ejemplares similares
-
Co‐targeting FAK and Gli1 inhibits the tumor‐associated macrophages‐released CCL22‐mediated esophageal squamous cell carcinoma malignancy
por: Chen, Jie, et al.
Publicado: (2023) -
Chrysin serves as a novel inhibitor of DGKα/FAK interaction to suppress the malignancy of esophageal squamous cell carcinoma (ESCC)
por: Chen, Jie, et al.
Publicado: (2021) -
Nicotine Activates YAP1 through nAChRs Mediated Signaling in Esophageal Squamous Cell Cancer (ESCC)
por: Zhao, Yue, et al.
Publicado: (2014) -
CCL22-Polarized TAMs to M2a Macrophages in Cervical Cancer In Vitro Model
por: Wang, Qun, et al.
Publicado: (2022) -
PAFR/Stat3 axis maintains the symbiotic ecosystem between tumor and stroma to facilitate tumor malignancy
por: Zhao, Di, et al.
Publicado: (2023)