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TLR agonists induce sustained IgG to hemagglutinin stem and modulate T cells following newborn vaccination
The newborn immune system is characterized by diminished immune responses that leave infants vulnerable to virus-mediated disease and make vaccination more challenging. Optimal vaccination strategies for influenza A virus (IAV) in newborns should result in robust levels of protective antibodies, inc...
Autores principales: | Clemens, Elene A., Holbrook, Beth C., McNeilly, Brendan, Kanekiyo, Masaru, Graham, Barney S., Alexander-Miller, Martha A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424286/ https://www.ncbi.nlm.nih.gov/pubmed/36038596 http://dx.doi.org/10.1038/s41541-022-00523-8 |
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