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High dose androgen suppresses natural killer cytotoxicity of castration-resistant prostate cancer cells via altering AR/circFKBP5/miRNA-513a-5p/PD-L1 signals

Most advanced prostate cancer (PCa) patients initially respond well to androgen deprivation therapy, but almost all eventually develop castration-resistant prostate cancer (CRPC). Early studies indicated the bipolar androgen therapy via a cycling of high dose and low dose of androgen to suppress PCa...

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Detalles Bibliográficos
Autores principales:	Tang, Min, Sun, Yin, Huang, Chi-Ping, Chen, Lei, Liu, Bianjiang, You, Bosen, Wang, Zengjun, Chang, Chawnshang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424293/ https://www.ncbi.nlm.nih.gov/pubmed/36038573 http://dx.doi.org/10.1038/s41419-022-04956-w

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