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Insulin signaling as a therapeutic mechanism of lithium in bipolar disorder

In this paper, we propose that lithium may exert its therapeutic effect in bipolar disorder by acting on insulin signaling pathways. Specifically, we assess the importance of the phosphatidylinositol 3-kinase/Protein Kinase B (PI3K/Akt) insulin signaling pathway and we assess how the action of lithi...

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Detalles Bibliográficos
Autores principales: Campbell, Iain H., Campbell, Harry, Smith, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424309/
https://www.ncbi.nlm.nih.gov/pubmed/36038539
http://dx.doi.org/10.1038/s41398-022-02122-6

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