Effectiveness of PARP inhibition in enhancing the radiosensitivity of 3D spheroids of head and neck squamous cell carcinoma

A critical risk factor for head and neck squamous cell carcinoma (HNSCC), particularly of the oropharynx, and the response to radiotherapy is human papillomavirus (HPV) type-16/18 infection. Specifically, HPV-positive HNSCC display increased radiosensitivity and improved outcomes, which has been lin...

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Detalles Bibliográficos
Autores principales: Zhou, Chumin, Fabbrizi, Maria Rita, Hughes, Jonathan R., Grundy, Gabrielle J., Parsons, Jason L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424551/
https://www.ncbi.nlm.nih.gov/pubmed/36052247
http://dx.doi.org/10.3389/fonc.2022.940377

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