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Physiologically based pharmacokinetic modeling of daptomycin dose optimization in pediatric patients with renal impairment

Background and Objective: Daptomycin is used to treat Gram-positive infections in adults and children and its dosing varies among different age groups. We focused on the pharmacokinetics of daptomycin in children with renal impairment, which has not been evaluated. Methods: A physiologically based p...

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Detalles Bibliográficos
Autores principales:	Ye, Lingling, You, Xiang, Zhou, Jie, Wu, Chaohui, Ke, Meng, Wu, Wanhong, Huang, Pinfang, Lin, Cuihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424659/ https://www.ncbi.nlm.nih.gov/pubmed/36052120 http://dx.doi.org/10.3389/fphar.2022.838599

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