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A Kunitz-type inhibitor from tick salivary glands: A promising novel antitumor drug candidate
Salivary glands are vital structures responsible for successful tick feeding. The saliva of ticks contains numerous active molecules that participate in several physiological processes. A Kunitz-type factor Xa (FXa) inhibitor, similar to the tissue factor pathway inhibitor (TFPI) precursor, was iden...
Autores principales: | Lobba, Aline R. M., Alvarez-Flores, Miryam Paola, Fessel, Melissa Regina, Buri, Marcus Vinicius, Oliveira, Douglas S., Gomes, Renata N., Cunegundes, Priscila S., DeOcesano-Pereira, Carlos, Cinel, Victor D., Chudzinski-Tavassi, Ana M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424826/ https://www.ncbi.nlm.nih.gov/pubmed/36052162 http://dx.doi.org/10.3389/fmolb.2022.936107 |
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