Enhancing arginase 2 expression using target site blockers as a strategy to modulate macrophage phenotype

Macrophages are plastic cells playing a crucial role in innate immunity. While fundamental in responding to infections, when persistently maintained in a pro-inflammatory state they can initiate and sustain inflammatory diseases. Therefore, a strategy that reprograms pro-inflammatory macrophages tow...

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Detalles Bibliográficos
Autores principales: De Santi, Chiara, Nally, Frances K., Afzal, Remsha, Duffy, Conor P., Fitzsimons, Stephen, Annett, Stephanie L., Robson, Tracy, Dowling, Jennifer K., Cryan, Sally-Ann, McCoy, Claire E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424864/
https://www.ncbi.nlm.nih.gov/pubmed/36090747
http://dx.doi.org/10.1016/j.omtn.2022.08.004

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