The complex formation of MASP-3 with pattern recognition molecules of the lectin complement pathway retains MASP-3 in the circulation

The complement system plays an important role in host defense and is activated via three different activation pathways. We have previously reported that mannose-binding lectin-associated serine protease (MASP)-3, unlike its splicing variant MASP-1, circulates in an active form and is essential for t...

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Detalles Bibliográficos
Autores principales: Kusakari, Kohei, Machida, Takeshi, Ishida, Yumi, Omori, Tomoko, Suzuki, Toshiyuki, Sekimata, Masayuki, Wada, Ikuo, Fujita, Teizo, Sekine, Hideharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425028/
https://www.ncbi.nlm.nih.gov/pubmed/36052069
http://dx.doi.org/10.3389/fimmu.2022.907023

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