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Ferroportin-dependent ferroptosis induced by ellagic acid retards liver fibrosis by impairing the SNARE complexes formation

Chronic liver injury causing liver fibrosis is a major cause of morbidity and mortality worldwide. Targeting the suppression of hepatic stellate cell (HSC) activation is recognized as an effective strategy for the treatment of liver fibrosis. Ellagic acid (EA), a natural polyphenol product isolated...

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Detalles Bibliográficos
Autores principales: Li, Lihua, Wang, Kunpeng, Jia, Rongjun, xie, Jing, Ma, Liman, Hao, Zhiqing, Zhang, Weiwei, Mo, Jinggang, Ren, Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425030/
https://www.ncbi.nlm.nih.gov/pubmed/36029649
http://dx.doi.org/10.1016/j.redox.2022.102435