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Deconvolution of B cell receptor repertoire in multiple sclerosis patients revealed a delay in tBreg maturation

BACKGROUND: B lymphocytes play a pivotal regulatory role in the development of the immune response. It was previously shown that deficiency in B regulatory cells (Bregs) or a decrease in their anti-inflammatory activity can lead to immunological dysfunctions. However, the exact mechanisms of Bregs d...

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Detalles Bibliográficos
Autores principales:	Lomakin, Yakov A., Zvyagin, Ivan V., Ovchinnikova, Leyla A., Kabilov, Marsel R., Staroverov, Dmitriy B., Mikelov, Artem, Tupikin, Alexey E., Zakharova, Maria Y., Bykova, Nadezda A., Mukhina, Vera S., Favorov, Alexander V., Ivanova, Maria, Simaniv, Taras, Rubtsov, Yury P., Chudakov, Dmitriy M., Zakharova, Maria N., Illarioshkin, Sergey N., Belogurov, Alexey A., Gabibov, Alexander G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425031/ https://www.ncbi.nlm.nih.gov/pubmed/36052064 http://dx.doi.org/10.3389/fimmu.2022.803229

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