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Spatial biology analysis reveals B cell follicles in secondary lymphoid structures may regulate anti-tumor responses at initial melanoma diagnosis

INTRODUCTION: B cells are key regulators of immune responses in melanoma. We aimed to explore differences in the histologic location and activation status of B cell follicles in sentinel lymph nodes (SLN) of melanoma patients. METHODS: Flow cytometry was performed on fresh tumor draining lymph nodes...

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Detalles Bibliográficos
Autores principales: Therien, Aaron D., Beasley, Georgia M., Rhodin, Kristen E., Farrow, Norma E., Tyler, Douglas S., Boczkowski, David, Al-Rohil, Rami N., Holl, Eda K., Nair, Smita K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425113/
https://www.ncbi.nlm.nih.gov/pubmed/36052068
http://dx.doi.org/10.3389/fimmu.2022.952220