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Spatial biology analysis reveals B cell follicles in secondary lymphoid structures may regulate anti-tumor responses at initial melanoma diagnosis
INTRODUCTION: B cells are key regulators of immune responses in melanoma. We aimed to explore differences in the histologic location and activation status of B cell follicles in sentinel lymph nodes (SLN) of melanoma patients. METHODS: Flow cytometry was performed on fresh tumor draining lymph nodes...
Autores principales: | Therien, Aaron D., Beasley, Georgia M., Rhodin, Kristen E., Farrow, Norma E., Tyler, Douglas S., Boczkowski, David, Al-Rohil, Rami N., Holl, Eda K., Nair, Smita K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425113/ https://www.ncbi.nlm.nih.gov/pubmed/36052068 http://dx.doi.org/10.3389/fimmu.2022.952220 |
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