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PYK2 mediates the BRAF inhibitor (vermurafenib)-induced invadopodia formation and metastasis in melanomas

OBJECTIVE: The BRAF inhibitor, vemurafenib, has been widely used in the treatment of patients with melanoma-bearing BRAF(V600E) mutations. While the initial response to vemurafenib is usually excellent, the majority of patients eventually develop resistance and metastatic disease. However, the under...

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Detalles Bibliográficos
Autores principales:	Shen, Junling, Yang, Jilong, Sang, Lei, Sun, Rui, Bai, Weiyu, Wang, Chao, Sun, Yan, Sun, Jianwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Compuscript 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425182/ https://www.ncbi.nlm.nih.gov/pubmed/34570440 http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0294

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