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High prevalence and incidence of HIV-1 in a counseling and testing center in the city of Itajaí, Brazil
Itajaí is a port city in southern Brazil with one of the highest incidence and mortality rates from AIDS in the country. The prevalence and incidence of HIV infection were investigated in 1085 of 3196 new HIV-1 infection cases evaluated in the counseling and testing center of Itajaí from January 200...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425333/ https://www.ncbi.nlm.nih.gov/pubmed/26361837 http://dx.doi.org/10.1016/j.bjid.2015.08.001 |
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author | Grinberg, Gorki Giron, Leila Bertoni Knoll, Rosalie Kupka Galinskas, Juliana Camargo, Michelle Arif, Muhammad Shoaib Samer, Sadia Janini, Luiz Mario Ramos Sucupira, Maria Cecilia Araripe Diaz, Ricardo Sobhie |
author_facet | Grinberg, Gorki Giron, Leila Bertoni Knoll, Rosalie Kupka Galinskas, Juliana Camargo, Michelle Arif, Muhammad Shoaib Samer, Sadia Janini, Luiz Mario Ramos Sucupira, Maria Cecilia Araripe Diaz, Ricardo Sobhie |
author_sort | Grinberg, Gorki |
collection | PubMed |
description | Itajaí is a port city in southern Brazil with one of the highest incidence and mortality rates from AIDS in the country. The prevalence and incidence of HIV infection were investigated in 1085 of 3196 new HIV-1 infection cases evaluated in the counseling and testing center of Itajaí from January 2002 to August 2008. Recent infections were assessed using the BED™, and pol region sequencing was performed in 76 samples. The prevalence ranged from 3.08% to 6.17% among women and from 10.26% to 17.36% among men. A total of 17% of infections were classified as recent, with annual incidence varying from 1.6% to 4.8 per 100 patient/year among women and from 2.05% to 8.5 per 100 patient/year among men. Pol sequences were obtained from 38 randomly recent infections selected individuals: 71% were infected by subtype C, 24% B, 2% D, and 2% F1. Among 38 subjects with established infection, 76% were subtype C, and 24% B. Transmitted drug resistance was detected in 18.4% of recent infection subjects (7.8% to nucleoside analog reverse-transcriptase inhibitors, 5.2% to non-nucleoside reverse-transcriptase inhibitors, and 5.2% protease inhibitors) and 5.2% of subjects with established infection had nucleoside analog reverse-transcriptase inhibitors resistance. The high prevalence and incidence of HIV infection in this region is unprecedented in studies involving cases evaluated in the counseling and testing centers in Brazil. |
format | Online Article Text |
id | pubmed-9425333 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-94253332022-08-31 High prevalence and incidence of HIV-1 in a counseling and testing center in the city of Itajaí, Brazil Grinberg, Gorki Giron, Leila Bertoni Knoll, Rosalie Kupka Galinskas, Juliana Camargo, Michelle Arif, Muhammad Shoaib Samer, Sadia Janini, Luiz Mario Ramos Sucupira, Maria Cecilia Araripe Diaz, Ricardo Sobhie Braz J Infect Dis Original Article Itajaí is a port city in southern Brazil with one of the highest incidence and mortality rates from AIDS in the country. The prevalence and incidence of HIV infection were investigated in 1085 of 3196 new HIV-1 infection cases evaluated in the counseling and testing center of Itajaí from January 2002 to August 2008. Recent infections were assessed using the BED™, and pol region sequencing was performed in 76 samples. The prevalence ranged from 3.08% to 6.17% among women and from 10.26% to 17.36% among men. A total of 17% of infections were classified as recent, with annual incidence varying from 1.6% to 4.8 per 100 patient/year among women and from 2.05% to 8.5 per 100 patient/year among men. Pol sequences were obtained from 38 randomly recent infections selected individuals: 71% were infected by subtype C, 24% B, 2% D, and 2% F1. Among 38 subjects with established infection, 76% were subtype C, and 24% B. Transmitted drug resistance was detected in 18.4% of recent infection subjects (7.8% to nucleoside analog reverse-transcriptase inhibitors, 5.2% to non-nucleoside reverse-transcriptase inhibitors, and 5.2% protease inhibitors) and 5.2% of subjects with established infection had nucleoside analog reverse-transcriptase inhibitors resistance. The high prevalence and incidence of HIV infection in this region is unprecedented in studies involving cases evaluated in the counseling and testing centers in Brazil. Elsevier 2015-09-09 /pmc/articles/PMC9425333/ /pubmed/26361837 http://dx.doi.org/10.1016/j.bjid.2015.08.001 Text en © 2015 Elsevier Editora Ltda. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Article Grinberg, Gorki Giron, Leila Bertoni Knoll, Rosalie Kupka Galinskas, Juliana Camargo, Michelle Arif, Muhammad Shoaib Samer, Sadia Janini, Luiz Mario Ramos Sucupira, Maria Cecilia Araripe Diaz, Ricardo Sobhie High prevalence and incidence of HIV-1 in a counseling and testing center in the city of Itajaí, Brazil |
title | High prevalence and incidence of HIV-1 in a counseling and testing center in the city of Itajaí, Brazil |
title_full | High prevalence and incidence of HIV-1 in a counseling and testing center in the city of Itajaí, Brazil |
title_fullStr | High prevalence and incidence of HIV-1 in a counseling and testing center in the city of Itajaí, Brazil |
title_full_unstemmed | High prevalence and incidence of HIV-1 in a counseling and testing center in the city of Itajaí, Brazil |
title_short | High prevalence and incidence of HIV-1 in a counseling and testing center in the city of Itajaí, Brazil |
title_sort | high prevalence and incidence of hiv-1 in a counseling and testing center in the city of itajaí, brazil |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425333/ https://www.ncbi.nlm.nih.gov/pubmed/26361837 http://dx.doi.org/10.1016/j.bjid.2015.08.001 |
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