Abacavir-induced liver toxicity

Abacavir-induced liver toxicity is a rare event almost exclusively occurring in HLA B*5701-positive patients. Herein, we report one case of abnormal liver function tests occurring in a young HLA B*5701-negative woman on a stable nevirapine-based regimen with no history of liver problems or alcohol a...

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Autores principales: Pezzani, Maria Diletta, Resnati, Chiara, Di Cristo, Valentina, Riva, Agostino, Gervasoni, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425524/
https://www.ncbi.nlm.nih.gov/pubmed/27054757
http://dx.doi.org/10.1016/j.bjid.2016.03.002
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author Pezzani, Maria Diletta
Resnati, Chiara
Di Cristo, Valentina
Riva, Agostino
Gervasoni, Cristina
author_facet Pezzani, Maria Diletta
Resnati, Chiara
Di Cristo, Valentina
Riva, Agostino
Gervasoni, Cristina
author_sort Pezzani, Maria Diletta
collection PubMed
description Abacavir-induced liver toxicity is a rare event almost exclusively occurring in HLA B*5701-positive patients. Herein, we report one case of abnormal liver function tests occurring in a young HLA B*5701-negative woman on a stable nevirapine-based regimen with no history of liver problems or alcohol abuse after switching to abacavir from tenofovir. We also investigated the reasons for abacavir discontinuation in a cohort of patients treated with abacavir-lamivudine-nevirapine.
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spelling pubmed-94255242022-08-31 Abacavir-induced liver toxicity Pezzani, Maria Diletta Resnati, Chiara Di Cristo, Valentina Riva, Agostino Gervasoni, Cristina Braz J Infect Dis Case Report Abacavir-induced liver toxicity is a rare event almost exclusively occurring in HLA B*5701-positive patients. Herein, we report one case of abnormal liver function tests occurring in a young HLA B*5701-negative woman on a stable nevirapine-based regimen with no history of liver problems or alcohol abuse after switching to abacavir from tenofovir. We also investigated the reasons for abacavir discontinuation in a cohort of patients treated with abacavir-lamivudine-nevirapine. Elsevier 2016-04-04 /pmc/articles/PMC9425524/ /pubmed/27054757 http://dx.doi.org/10.1016/j.bjid.2016.03.002 Text en © 2016 Elsevier Editora Ltda. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Pezzani, Maria Diletta
Resnati, Chiara
Di Cristo, Valentina
Riva, Agostino
Gervasoni, Cristina
Abacavir-induced liver toxicity
title Abacavir-induced liver toxicity
title_full Abacavir-induced liver toxicity
title_fullStr Abacavir-induced liver toxicity
title_full_unstemmed Abacavir-induced liver toxicity
title_short Abacavir-induced liver toxicity
title_sort abacavir-induced liver toxicity
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425524/
https://www.ncbi.nlm.nih.gov/pubmed/27054757
http://dx.doi.org/10.1016/j.bjid.2016.03.002
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