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Micrographic Surgery Allows Fascia Preservation in Dermatofibrosarcoma Protuberans
Removal of the deep fascia is recommended in therapy for dermatofibrosarcoma protuberans, but its necessity in the context of micrographic surgery is unclear. A retrospective clinicopathological analysis of 48 patients with dermatofibrosarcoma protuberans treated by micrographic surgery was performe...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Publication of Acta Dermato-Venereologica
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425625/ https://www.ncbi.nlm.nih.gov/pubmed/34490467 http://dx.doi.org/10.2340/00015555-3915 |
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author | GASSENMAIER, Maximilian WEBER, Erik LEITER, Ulrike HAHN, Matthias FORCHHAMMER, Stephan HÄFNER, Hans-Martin SCHEU, Alexander GARBE, Claus SCHNABL, Saskia Maria |
author_facet | GASSENMAIER, Maximilian WEBER, Erik LEITER, Ulrike HAHN, Matthias FORCHHAMMER, Stephan HÄFNER, Hans-Martin SCHEU, Alexander GARBE, Claus SCHNABL, Saskia Maria |
author_sort | GASSENMAIER, Maximilian |
collection | PubMed |
description | Removal of the deep fascia is recommended in therapy for dermatofibrosarcoma protuberans, but its necessity in the context of micrographic surgery is unclear. A retrospective clinicopathological analysis of 48 patients with dermatofibrosarcoma protuberans treated by micrographic surgery was performed, to determine in which tumours fascia preservation was feasible and safe. Histologically, 93% of tumours on the trunk and extremities and 14% of tumours in the head and neck region were fully located above the fascia. Localization on the head and neck was the only significant risk factor for tumour extension beyond the subcutis (p<0.001). Overall, 44% of tumours were completely excised above the fascia and 56% with deeper excisions. Two deeply infiltrating tumours (4%) on the head recurred, but in none of these lesions was the fascia spared. These results show that micrographic surgery allows fascia preservation in superficial tumours outside the head and neck region. |
format | Online Article Text |
id | pubmed-9425625 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Society for Publication of Acta Dermato-Venereologica |
record_format | MEDLINE/PubMed |
spelling | pubmed-94256252022-10-20 Micrographic Surgery Allows Fascia Preservation in Dermatofibrosarcoma Protuberans GASSENMAIER, Maximilian WEBER, Erik LEITER, Ulrike HAHN, Matthias FORCHHAMMER, Stephan HÄFNER, Hans-Martin SCHEU, Alexander GARBE, Claus SCHNABL, Saskia Maria Acta Derm Venereol Clinical Report Removal of the deep fascia is recommended in therapy for dermatofibrosarcoma protuberans, but its necessity in the context of micrographic surgery is unclear. A retrospective clinicopathological analysis of 48 patients with dermatofibrosarcoma protuberans treated by micrographic surgery was performed, to determine in which tumours fascia preservation was feasible and safe. Histologically, 93% of tumours on the trunk and extremities and 14% of tumours in the head and neck region were fully located above the fascia. Localization on the head and neck was the only significant risk factor for tumour extension beyond the subcutis (p<0.001). Overall, 44% of tumours were completely excised above the fascia and 56% with deeper excisions. Two deeply infiltrating tumours (4%) on the head recurred, but in none of these lesions was the fascia spared. These results show that micrographic surgery allows fascia preservation in superficial tumours outside the head and neck region. Society for Publication of Acta Dermato-Venereologica 2021-09-28 /pmc/articles/PMC9425625/ /pubmed/34490467 http://dx.doi.org/10.2340/00015555-3915 Text en © 2021 Acta Dermato-Venereologica https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the CC BY-NC license |
spellingShingle | Clinical Report GASSENMAIER, Maximilian WEBER, Erik LEITER, Ulrike HAHN, Matthias FORCHHAMMER, Stephan HÄFNER, Hans-Martin SCHEU, Alexander GARBE, Claus SCHNABL, Saskia Maria Micrographic Surgery Allows Fascia Preservation in Dermatofibrosarcoma Protuberans |
title | Micrographic Surgery Allows Fascia Preservation in Dermatofibrosarcoma Protuberans |
title_full | Micrographic Surgery Allows Fascia Preservation in Dermatofibrosarcoma Protuberans |
title_fullStr | Micrographic Surgery Allows Fascia Preservation in Dermatofibrosarcoma Protuberans |
title_full_unstemmed | Micrographic Surgery Allows Fascia Preservation in Dermatofibrosarcoma Protuberans |
title_short | Micrographic Surgery Allows Fascia Preservation in Dermatofibrosarcoma Protuberans |
title_sort | micrographic surgery allows fascia preservation in dermatofibrosarcoma protuberans |
topic | Clinical Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425625/ https://www.ncbi.nlm.nih.gov/pubmed/34490467 http://dx.doi.org/10.2340/00015555-3915 |
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