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Micrographic Surgery Allows Fascia Preservation in Dermatofibrosarcoma Protuberans

Removal of the deep fascia is recommended in therapy for dermatofibrosarcoma protuberans, but its necessity in the context of micrographic surgery is unclear. A retrospective clinicopathological analysis of 48 patients with dermatofibrosarcoma protuberans treated by micrographic surgery was performe...

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Autores principales: GASSENMAIER, Maximilian, WEBER, Erik, LEITER, Ulrike, HAHN, Matthias, FORCHHAMMER, Stephan, HÄFNER, Hans-Martin, SCHEU, Alexander, GARBE, Claus, SCHNABL, Saskia Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Publication of Acta Dermato-Venereologica 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425625/
https://www.ncbi.nlm.nih.gov/pubmed/34490467
http://dx.doi.org/10.2340/00015555-3915
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author GASSENMAIER, Maximilian
WEBER, Erik
LEITER, Ulrike
HAHN, Matthias
FORCHHAMMER, Stephan
HÄFNER, Hans-Martin
SCHEU, Alexander
GARBE, Claus
SCHNABL, Saskia Maria
author_facet GASSENMAIER, Maximilian
WEBER, Erik
LEITER, Ulrike
HAHN, Matthias
FORCHHAMMER, Stephan
HÄFNER, Hans-Martin
SCHEU, Alexander
GARBE, Claus
SCHNABL, Saskia Maria
author_sort GASSENMAIER, Maximilian
collection PubMed
description Removal of the deep fascia is recommended in therapy for dermatofibrosarcoma protuberans, but its necessity in the context of micrographic surgery is unclear. A retrospective clinicopathological analysis of 48 patients with dermatofibrosarcoma protuberans treated by micrographic surgery was performed, to determine in which tumours fascia preservation was feasible and safe. Histologically, 93% of tumours on the trunk and extremities and 14% of tumours in the head and neck region were fully located above the fascia. Localization on the head and neck was the only significant risk factor for tumour extension beyond the subcutis (p<0.001). Overall, 44% of tumours were completely excised above the fascia and 56% with deeper excisions. Two deeply infiltrating tumours (4%) on the head recurred, but in none of these lesions was the fascia spared. These results show that micrographic surgery allows fascia preservation in superficial tumours outside the head and neck region.
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spelling pubmed-94256252022-10-20 Micrographic Surgery Allows Fascia Preservation in Dermatofibrosarcoma Protuberans GASSENMAIER, Maximilian WEBER, Erik LEITER, Ulrike HAHN, Matthias FORCHHAMMER, Stephan HÄFNER, Hans-Martin SCHEU, Alexander GARBE, Claus SCHNABL, Saskia Maria Acta Derm Venereol Clinical Report Removal of the deep fascia is recommended in therapy for dermatofibrosarcoma protuberans, but its necessity in the context of micrographic surgery is unclear. A retrospective clinicopathological analysis of 48 patients with dermatofibrosarcoma protuberans treated by micrographic surgery was performed, to determine in which tumours fascia preservation was feasible and safe. Histologically, 93% of tumours on the trunk and extremities and 14% of tumours in the head and neck region were fully located above the fascia. Localization on the head and neck was the only significant risk factor for tumour extension beyond the subcutis (p<0.001). Overall, 44% of tumours were completely excised above the fascia and 56% with deeper excisions. Two deeply infiltrating tumours (4%) on the head recurred, but in none of these lesions was the fascia spared. These results show that micrographic surgery allows fascia preservation in superficial tumours outside the head and neck region. Society for Publication of Acta Dermato-Venereologica 2021-09-28 /pmc/articles/PMC9425625/ /pubmed/34490467 http://dx.doi.org/10.2340/00015555-3915 Text en © 2021 Acta Dermato-Venereologica https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the CC BY-NC license
spellingShingle Clinical Report
GASSENMAIER, Maximilian
WEBER, Erik
LEITER, Ulrike
HAHN, Matthias
FORCHHAMMER, Stephan
HÄFNER, Hans-Martin
SCHEU, Alexander
GARBE, Claus
SCHNABL, Saskia Maria
Micrographic Surgery Allows Fascia Preservation in Dermatofibrosarcoma Protuberans
title Micrographic Surgery Allows Fascia Preservation in Dermatofibrosarcoma Protuberans
title_full Micrographic Surgery Allows Fascia Preservation in Dermatofibrosarcoma Protuberans
title_fullStr Micrographic Surgery Allows Fascia Preservation in Dermatofibrosarcoma Protuberans
title_full_unstemmed Micrographic Surgery Allows Fascia Preservation in Dermatofibrosarcoma Protuberans
title_short Micrographic Surgery Allows Fascia Preservation in Dermatofibrosarcoma Protuberans
title_sort micrographic surgery allows fascia preservation in dermatofibrosarcoma protuberans
topic Clinical Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425625/
https://www.ncbi.nlm.nih.gov/pubmed/34490467
http://dx.doi.org/10.2340/00015555-3915
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