Effect of polymyxin B-containing regimens on renal function for the treatment of carbapenem-resistant Enterobacteriacea mediastinitis()

A retrospective cohort study, were evaluated: polymyxin B plus aminoglycosides or polymyxin B plus other antibiotics. Any degree of acute kidney injury occurred in 26 (86.6%) patients. The median time to acute kidney injury was 6.0 (95% CI 3–14) days in the polymyxin-aminoglycoside containing regime...

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Detalles Bibliográficos
Autores principales: Abboud, Cely Saad, Rao, Gauri G., Souza, Ercilia E., Zavascki, Alexandre P., Kiffer, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425646/
https://www.ncbi.nlm.nih.gov/pubmed/29182906
http://dx.doi.org/10.1016/j.bjid.2017.10.006
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author Abboud, Cely Saad
Rao, Gauri G.
Souza, Ercilia E.
Zavascki, Alexandre P.
Kiffer, Carlos
author_facet Abboud, Cely Saad
Rao, Gauri G.
Souza, Ercilia E.
Zavascki, Alexandre P.
Kiffer, Carlos
author_sort Abboud, Cely Saad
collection PubMed
description A retrospective cohort study, were evaluated: polymyxin B plus aminoglycosides or polymyxin B plus other antibiotics. Any degree of acute kidney injury occurred in 26 (86.6%) patients. The median time to acute kidney injury was 6.0 (95% CI 3–14) days in the polymyxin-aminoglycoside containing regimen group, against 27.0 (95% CI 6–42) days in the polymyxin with other antimicrobial combinations group (p = 0.03). Polymyxin B with aminoglycosides group progressed faster to any degree of renal dysfunction.
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spelling pubmed-94256462022-08-31 Effect of polymyxin B-containing regimens on renal function for the treatment of carbapenem-resistant Enterobacteriacea mediastinitis() Abboud, Cely Saad Rao, Gauri G. Souza, Ercilia E. Zavascki, Alexandre P. Kiffer, Carlos Braz J Infect Dis Brief Communication A retrospective cohort study, were evaluated: polymyxin B plus aminoglycosides or polymyxin B plus other antibiotics. Any degree of acute kidney injury occurred in 26 (86.6%) patients. The median time to acute kidney injury was 6.0 (95% CI 3–14) days in the polymyxin-aminoglycoside containing regimen group, against 27.0 (95% CI 6–42) days in the polymyxin with other antimicrobial combinations group (p = 0.03). Polymyxin B with aminoglycosides group progressed faster to any degree of renal dysfunction. Elsevier 2017-11-26 /pmc/articles/PMC9425646/ /pubmed/29182906 http://dx.doi.org/10.1016/j.bjid.2017.10.006 Text en © 2017 Sociedade Brasileira de Infectologia. Published by Elsevier Editora Ltda. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Brief Communication
Abboud, Cely Saad
Rao, Gauri G.
Souza, Ercilia E.
Zavascki, Alexandre P.
Kiffer, Carlos
Effect of polymyxin B-containing regimens on renal function for the treatment of carbapenem-resistant Enterobacteriacea mediastinitis()
title Effect of polymyxin B-containing regimens on renal function for the treatment of carbapenem-resistant Enterobacteriacea mediastinitis()
title_full Effect of polymyxin B-containing regimens on renal function for the treatment of carbapenem-resistant Enterobacteriacea mediastinitis()
title_fullStr Effect of polymyxin B-containing regimens on renal function for the treatment of carbapenem-resistant Enterobacteriacea mediastinitis()
title_full_unstemmed Effect of polymyxin B-containing regimens on renal function for the treatment of carbapenem-resistant Enterobacteriacea mediastinitis()
title_short Effect of polymyxin B-containing regimens on renal function for the treatment of carbapenem-resistant Enterobacteriacea mediastinitis()
title_sort effect of polymyxin b-containing regimens on renal function for the treatment of carbapenem-resistant enterobacteriacea mediastinitis()
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425646/
https://www.ncbi.nlm.nih.gov/pubmed/29182906
http://dx.doi.org/10.1016/j.bjid.2017.10.006
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