Genomic and epidemiologic surveillance of SARS-CoV-2 in Southern Brazil and identification of a new Omicron-L452R sublineage

Recently, SARS-CoV-2 Omicron variant (B.1.1.529) was first identified in Botswana in November 2021. In a short period of time, this highly mutated variant replaced the previous dominant Delta variant, causing an exponential increase in the number of COVID-19 cases, resulting in a new wave of pandemi...

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Detalles Bibliográficos
Autores principales: da Silva, Mariana Soares, Gularte, Juliana Schons, Filippi, Micheli, Demoliner, Meriane, Girardi, Viviane, Mosena, Ana Cristina Sbaraini, Pereira, Vyctoria Malayhka de Abreu Góes, Hansen, Alana Witt, Weber, Matheus Nunes, de Almeida, Paula Rodrigues, Fleck, Juliane Deise, Bó, Andrea Gurgel Batista Leite Dal, Jones, Marcus Herbert, Friedrich, Frederico, Filho, Luiz Amorim, Klamt, Fábio, Spilki, Fernando Rosado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425700/
https://www.ncbi.nlm.nih.gov/pubmed/36055471
http://dx.doi.org/10.1016/j.virusres.2022.198907
Descripción
Sumario:Recently, SARS-CoV-2 Omicron variant (B.1.1.529) was first identified in Botswana in November 2021. In a short period of time, this highly mutated variant replaced the previous dominant Delta variant, causing an exponential increase in the number of COVID-19 cases, resulting in a new wave of pandemic. This current research article aims to analyze and summarize information about the genetic characteristics, amino acid mutations and epidemiological data providing scientific findings to enrich the SARS-CoV-2 knowledge. More importantly, we describe here, for the first time, the identification of a new Omicron variant of concern: Omicron-L452R in Brazil.

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