Notch signaling mutations increase intra-tumor chemokine expression and predict response to immunotherapy in colorectal cancer

BACKGROUND: The Notch signaling mutation is associated with enhanced anti-tumor immune response in colorectal cancer (CRC). In this study, we aim to investigate the underlying mechanism and the predictive potential of Notch signaling mutation for responding to immunotherapy in CRC. METHODS: We analy...

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Detalles Bibliográficos
Autores principales: Wang, Fei, Huang, Chuan, Long, Jie, Zhao, Zhi-Bin, Ma, Hai-Qing, Yao, Xue-Qing, Li, Liang, Lian, Zhe-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426242/
https://www.ncbi.nlm.nih.gov/pubmed/36038820
http://dx.doi.org/10.1186/s12885-022-10032-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426242/
https://www.ncbi.nlm.nih.gov/pubmed/36038820
http://dx.doi.org/10.1186/s12885-022-10032-5

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