Cargando…

Gas chromatography-mass spectrometry (GC–MS) profiling of aqueous methanol fraction of Plagiochasma appendiculatum Lehm. & Lindenb. and Sphagnum fimbriatum Wilson for probable antiviral potential

The bryophytes consist of liverworts, mosses, and hornworts, among which the liverworts are quite different in having cellular oil bodies and contain numerous terpenoids, acetogenins, quinones, phenylpropanoids, flavonoids, etc. These metabolites exhibit interesting biological activity such as aller...

Descripción completa

Detalles Bibliográficos
Autores principales: Joshi, Supriya, Singh, Swati, Sharma, Rimjhim, Vats, Sharad, Alam, Afroz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426370/
https://www.ncbi.nlm.nih.gov/pubmed/36061344
http://dx.doi.org/10.1007/s42535-022-00458-4
_version_ 1784778663847264256
author Joshi, Supriya
Singh, Swati
Sharma, Rimjhim
Vats, Sharad
Alam, Afroz
author_facet Joshi, Supriya
Singh, Swati
Sharma, Rimjhim
Vats, Sharad
Alam, Afroz
author_sort Joshi, Supriya
collection PubMed
description The bryophytes consist of liverworts, mosses, and hornworts, among which the liverworts are quite different in having cellular oil bodies and contain numerous terpenoids, acetogenins, quinones, phenylpropanoids, flavonoids, etc. These metabolites exhibit interesting biological activity such as allergenic response, insecticide, cytotoxic, neurotrophic, antimicrobial, and anti-HIV actions, etc. Though several bioactive compounds have been isolated in many liverworts, yet most of the liverworts have been unexplored till date regarding their phytochemistry. The ability of liverworts to generate a wide range of important phytochemicals makes them a hoard of bioactive compounds. In the past, a few species of bryophytes have been evaluated against a few viruses and interesting results were obtained that showed their role as an immunity enhancer against viral infection. The phytoconstituents found in liverworts and mosses can be useful to increase human immunity against a variety of viruses, including SARS-CoV-2. Keeping this in view, one of the most developed and robust metabolomics technologies, Gas chromatography-mass spectroscopy (GC–MS) was used to estimate the various phytoconstituents found in a commonly growing thalloid liverwort, Plagiochasma appendiculatum, and moss Sphagnum fimbriatum. The obtained profiles were appraised for their bioactive potential and probable role as antiviral agents.
format Online
Article
Text
id pubmed-9426370
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Springer Nature Singapore
record_format MEDLINE/PubMed
spelling pubmed-94263702022-08-30 Gas chromatography-mass spectrometry (GC–MS) profiling of aqueous methanol fraction of Plagiochasma appendiculatum Lehm. & Lindenb. and Sphagnum fimbriatum Wilson for probable antiviral potential Joshi, Supriya Singh, Swati Sharma, Rimjhim Vats, Sharad Alam, Afroz Vegetos Research Articles The bryophytes consist of liverworts, mosses, and hornworts, among which the liverworts are quite different in having cellular oil bodies and contain numerous terpenoids, acetogenins, quinones, phenylpropanoids, flavonoids, etc. These metabolites exhibit interesting biological activity such as allergenic response, insecticide, cytotoxic, neurotrophic, antimicrobial, and anti-HIV actions, etc. Though several bioactive compounds have been isolated in many liverworts, yet most of the liverworts have been unexplored till date regarding their phytochemistry. The ability of liverworts to generate a wide range of important phytochemicals makes them a hoard of bioactive compounds. In the past, a few species of bryophytes have been evaluated against a few viruses and interesting results were obtained that showed their role as an immunity enhancer against viral infection. The phytoconstituents found in liverworts and mosses can be useful to increase human immunity against a variety of viruses, including SARS-CoV-2. Keeping this in view, one of the most developed and robust metabolomics technologies, Gas chromatography-mass spectroscopy (GC–MS) was used to estimate the various phytoconstituents found in a commonly growing thalloid liverwort, Plagiochasma appendiculatum, and moss Sphagnum fimbriatum. The obtained profiles were appraised for their bioactive potential and probable role as antiviral agents. Springer Nature Singapore 2022-08-30 2023 /pmc/articles/PMC9426370/ /pubmed/36061344 http://dx.doi.org/10.1007/s42535-022-00458-4 Text en © The Author(s) under exclusive licence to Society for Plant Research 2022, Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Research Articles
Joshi, Supriya
Singh, Swati
Sharma, Rimjhim
Vats, Sharad
Alam, Afroz
Gas chromatography-mass spectrometry (GC–MS) profiling of aqueous methanol fraction of Plagiochasma appendiculatum Lehm. & Lindenb. and Sphagnum fimbriatum Wilson for probable antiviral potential
title Gas chromatography-mass spectrometry (GC–MS) profiling of aqueous methanol fraction of Plagiochasma appendiculatum Lehm. & Lindenb. and Sphagnum fimbriatum Wilson for probable antiviral potential
title_full Gas chromatography-mass spectrometry (GC–MS) profiling of aqueous methanol fraction of Plagiochasma appendiculatum Lehm. & Lindenb. and Sphagnum fimbriatum Wilson for probable antiviral potential
title_fullStr Gas chromatography-mass spectrometry (GC–MS) profiling of aqueous methanol fraction of Plagiochasma appendiculatum Lehm. & Lindenb. and Sphagnum fimbriatum Wilson for probable antiviral potential
title_full_unstemmed Gas chromatography-mass spectrometry (GC–MS) profiling of aqueous methanol fraction of Plagiochasma appendiculatum Lehm. & Lindenb. and Sphagnum fimbriatum Wilson for probable antiviral potential
title_short Gas chromatography-mass spectrometry (GC–MS) profiling of aqueous methanol fraction of Plagiochasma appendiculatum Lehm. & Lindenb. and Sphagnum fimbriatum Wilson for probable antiviral potential
title_sort gas chromatography-mass spectrometry (gc–ms) profiling of aqueous methanol fraction of plagiochasma appendiculatum lehm. & lindenb. and sphagnum fimbriatum wilson for probable antiviral potential
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426370/
https://www.ncbi.nlm.nih.gov/pubmed/36061344
http://dx.doi.org/10.1007/s42535-022-00458-4
work_keys_str_mv AT joshisupriya gaschromatographymassspectrometrygcmsprofilingofaqueousmethanolfractionofplagiochasmaappendiculatumlehmlindenbandsphagnumfimbriatumwilsonforprobableantiviralpotential
AT singhswati gaschromatographymassspectrometrygcmsprofilingofaqueousmethanolfractionofplagiochasmaappendiculatumlehmlindenbandsphagnumfimbriatumwilsonforprobableantiviralpotential
AT sharmarimjhim gaschromatographymassspectrometrygcmsprofilingofaqueousmethanolfractionofplagiochasmaappendiculatumlehmlindenbandsphagnumfimbriatumwilsonforprobableantiviralpotential
AT vatssharad gaschromatographymassspectrometrygcmsprofilingofaqueousmethanolfractionofplagiochasmaappendiculatumlehmlindenbandsphagnumfimbriatumwilsonforprobableantiviralpotential
AT alamafroz gaschromatographymassspectrometrygcmsprofilingofaqueousmethanolfractionofplagiochasmaappendiculatumlehmlindenbandsphagnumfimbriatumwilsonforprobableantiviralpotential