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Leishmania donovani Impedes Antileishmanial Immunity by Suppressing Dendritic Cells via the TIM-3 Receptor

An immunological hallmark of visceral leishmaniasis (VL), caused by Leishmania donovani, is profound immunosuppression. However, the molecular basis for this immune dysfunction has remained ill defined. Since dendritic cells (DCs) normally initiate antileishmanial immune responses, we investigated w...

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Detalles Bibliográficos
Autores principales: Akhtar, Md. Naushad, Kumar, Sahil, Sen, Pradip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426438/
https://www.ncbi.nlm.nih.gov/pubmed/35924848
http://dx.doi.org/10.1128/mbio.03309-21

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