Cargando…
Genetic Interaction Analysis Reveals that Cryptococcus neoformans Utilizes Multiple Acetyl-CoA-Generating Pathways during Infection
Cryptococcus neoformans is an important human fungal pathogen for which the external environment is its primary niche. Previous work has shown that two nonessential acetyl-CoA metabolism enzymes, ATP-citrate lyase (ACL1) and acetyl-CoA synthetase (ACS1), play important roles in C. neoformans infecti...
Autores principales: | Alden, Katy M., Jezewski, Andrew J., Beattie, Sarah R., Fox, David, Krysan, Damian J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426453/ https://www.ncbi.nlm.nih.gov/pubmed/35766403 http://dx.doi.org/10.1128/mbio.01279-22 |
Ejemplares similares
-
Gluconate Kinase Is Required for Gluconate Assimilation and Sporulation in Cryptococcus neoformans
por: Jezewski, Andrew J., et al.
Publicado: (2022) -
Carbon Dioxide Potentiates Flucytosine Susceptibility in Cryptococcus neoformans
por: Jezewski, Andrew J., et al.
Publicado: (2023) -
FKS1 Is Required for Cryptococcus neoformans Fitness In Vivo: Application of Copper-Regulated Gene Expression to Mouse Models of Cryptococcosis
por: Beattie, Sarah R., et al.
Publicado: (2022) -
Cryptococcus neoformans adapts to the host environment through TOR-mediated remodeling of phospholipid asymmetry
por: Ristow, Laura C., et al.
Publicado: (2023) -
Structural Characterization of the Reaction and Substrate
Specificity Mechanisms of Pathogenic Fungal Acetyl-CoA Synthetases
por: Jezewski, Andrew J., et al.
Publicado: (2021)