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Highly Variable Expression of Merozoite Surface Protein MSPDBL2 in Diverse Plasmodium falciparum Clinical Isolates and Transcriptome Scans for Correlating Genes

The merozoite surface protein MSPDBL2 of Plasmodium falciparum is under strong balancing selection and is a target of naturally acquired antibodies. Remarkably, MSPDBL2 is expressed in only a minority of mature schizonts of any cultured parasite line, and mspdbl2 gene transcription increases in resp...

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Detalles Bibliográficos
Autores principales: Hocking, Suzanne E., Stewart, Lindsay B., Freville, Aline, Reid, Adam J., Tarr, Sarah J., Tetteh, Kevin K. A., Flueck, Christian, Ahouidi, Ambroise D., Amambua-Ngwa, Alfred, Diakite, Mahamadou, Awandare, Gordon A., Conway, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426457/
https://www.ncbi.nlm.nih.gov/pubmed/35950755
http://dx.doi.org/10.1128/mbio.01948-22