Metalloproteinase-Dependent and TMPRSS2-Independent Cell Surface Entry Pathway of SARS-CoV-2 Requires the Furin Cleavage Site and the S2 Domain of Spike Protein

The ongoing global vaccination program to prevent SARS-CoV-2 infection, the causative agent of COVID-19, has had significant success. However, recently, virus variants that can evade the immunity in a host achieved through vaccination have emerged. Consequently, new therapeutic agents that can effic...

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Detalles Bibliográficos
Autores principales: Yamamoto, Mizuki, Gohda, Jin, Kobayashi, Ayako, Tomita, Keiko, Hirayama, Youko, Koshikawa, Naohiko, Seiki, Motoharu, Semba, Kentaro, Akiyama, Tetsu, Kawaguchi, Yasushi, Inoue, Jun-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426510/
https://www.ncbi.nlm.nih.gov/pubmed/35708281
http://dx.doi.org/10.1128/mbio.00519-22

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