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Metabolite Damage and Damage Control in a Minimal Genome

Analysis of the genes retained in the minimized Mycoplasma JCVI-Syn3A genome established that systems that repair or preempt metabolite damage are essential to life. Several genes known to have such functions were identified and experimentally validated, including 5-formyltetrahydrofolate cycloligas...

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Detalles Bibliográficos
Autores principales:	Haas, Drago, Thamm, Antje M., Sun, Jiayi, Huang, Lili, Sun, Lijie, Beaudoin, Guillaume A. W., Wise, Kim S., Lerma-Ortiz, Claudia, Bruner, Steven D., Breuer, Marian, Luthey-Schulten, Zaida, Lin, Jiusheng, Wilson, Mark A., Brown, Greg, Yakunin, Alexander F., Kurilyak, Inna, Folz, Jacob, Fiehn, Oliver, Glass, John I., Hanson, Andrew D., Henry, Christopher S., de Crécy-Lagard, Valérie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426524/ https://www.ncbi.nlm.nih.gov/pubmed/35862786 http://dx.doi.org/10.1128/mbio.01630-22

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