Staphylococcus aureus Infection Initiates Hypoxia-Mediated Transforming Growth Factor-β1 Upregulation to Trigger Osteomyelitis

Little is unknown about the regulatory mechanisms underlying the pathogenesis of osteomyelitis induced by Staphylococcus aureus. Hypoxia-inducible factor-1α (HIF-1α) and transforming growth factor β1 (TGF-β1) were both upregulated in S. aureus-infected MC3T3-E1 cells and osteomyelitis patients. HIF-...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Wei, Lin, Yiwei, Zong, Yang, Ma, Xin, Jiang, Chaolai, Shan, Haojie, Xia, Wenyang, Yin, Lifu, Wang, Nan, Zhou, Lihui, Zhou, Zubin, Yu, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426532/
https://www.ncbi.nlm.nih.gov/pubmed/35852344
http://dx.doi.org/10.1128/msystems.00380-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426532/
https://www.ncbi.nlm.nih.gov/pubmed/35852344
http://dx.doi.org/10.1128/msystems.00380-22

Ejemplares similares