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Interactions of Bacterial Toxin CNF1 and Host JAK1/2 Driven by Liquid-Liquid Phase Separation Enhance Macrophage Polarization

Urinary tract infections (UTIs) are a global public health concern, which is mainly caused by uropathogenic Escherichia coli (UPEC). Cytotoxic necrotizing factor 1 (CNF1) is a key UPEC toxin and regulates multiple host cellular processes through activating the Rho GTPases; however, the effect of CNF...

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Detalles Bibliográficos
Autores principales:	Sun, Xuan, Yang, Jianming, Deng, Xueqin, Wei, Yuting, Wang, Changying, Guo, Yaxiu, Yang, Huan, Yang, Liu, Miao, Chunhui, Lv, Junqiang, Xiao, Yawen, Zhang, Hong, Yao, Zhi, Wang, Quan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426534/ https://www.ncbi.nlm.nih.gov/pubmed/35766380 http://dx.doi.org/10.1128/mbio.01147-22

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