Glutamine Is Required for M1-like Polarization of Macrophages in Response to Mycobacterium tuberculosis Infection

In response to Mycobacterium tuberculosis infection, macrophages mount proinflammatory and antimicrobial responses similar to those observed in M1 macrophages activated by lipopolysaccharide (LPS) and interferon gamma (IFN-γ). A metabolic reprogramming to hypoxia-inducible-factor 1 (HIF-1)-mediated...

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Detalles Bibliográficos
Autores principales: Jiang, Qingkui, Qiu, Yunping, Kurland, Irwin J., Drlica, Karl, Subbian, Selvakumar, Tyagi, Sanjay, Shi, Lanbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426538/
https://www.ncbi.nlm.nih.gov/pubmed/35762591
http://dx.doi.org/10.1128/mbio.01274-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426538/
https://www.ncbi.nlm.nih.gov/pubmed/35762591
http://dx.doi.org/10.1128/mbio.01274-22

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