VEGF-Mediated Augmentation of Autophagic and Lysosomal Activity in Endothelial Cells Defends against Intracellular Streptococcus pyogenes

Group A Streptococcus (GAS), a deleterious human-pathogenic bacterium, causes life-threatening diseases such as sepsis and necrotic fasciitis. We recently reported that GAS survives and replicates within blood vessel endothelial cells because these cells are intrinsically defective in xenophagy. Bec...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Shiou-Ling, Omori, Hiroko, Zhou, Yi, Lin, Yee-Shin, Liu, Ching-Chuan, Wu, Jiunn-Jong, Noda, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426552/
https://www.ncbi.nlm.nih.gov/pubmed/35862783
http://dx.doi.org/10.1128/mbio.01233-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426552/
https://www.ncbi.nlm.nih.gov/pubmed/35862783
http://dx.doi.org/10.1128/mbio.01233-22

Ejemplares similares