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VEGF-Mediated Augmentation of Autophagic and Lysosomal Activity in Endothelial Cells Defends against Intracellular Streptococcus pyogenes
Group A Streptococcus (GAS), a deleterious human-pathogenic bacterium, causes life-threatening diseases such as sepsis and necrotic fasciitis. We recently reported that GAS survives and replicates within blood vessel endothelial cells because these cells are intrinsically defective in xenophagy. Bec...
Autores principales: | Lu, Shiou-Ling, Omori, Hiroko, Zhou, Yi, Lin, Yee-Shin, Liu, Ching-Chuan, Wu, Jiunn-Jong, Noda, Takeshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426552/ https://www.ncbi.nlm.nih.gov/pubmed/35862783 http://dx.doi.org/10.1128/mbio.01233-22 |
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