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VEGF-Mediated Augmentation of Autophagic and Lysosomal Activity in Endothelial Cells Defends against Intracellular Streptococcus pyogenes

Group A Streptococcus (GAS), a deleterious human-pathogenic bacterium, causes life-threatening diseases such as sepsis and necrotic fasciitis. We recently reported that GAS survives and replicates within blood vessel endothelial cells because these cells are intrinsically defective in xenophagy. Bec...

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Detalles Bibliográficos
Autores principales: Lu, Shiou-Ling, Omori, Hiroko, Zhou, Yi, Lin, Yee-Shin, Liu, Ching-Chuan, Wu, Jiunn-Jong, Noda, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426552/
https://www.ncbi.nlm.nih.gov/pubmed/35862783
http://dx.doi.org/10.1128/mbio.01233-22

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