The Plasmodium falciparum Nuclear Protein Phosphatase NIF4 Is Required for Efficient Merozoite Invasion and Regulates Artemisinin Sensitivity

Artemisinin resistance in Plasmodium falciparum has been associated with a mutation in the NLI-interacting factor-like phosphatase PfNIF4, in addition to the mutations in the Kelch13 protein as the major determinant. We found that PfNIF4 was predominantly expressed at the schizont stage and localize...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaotong, Li, Siqi, Wang, Chengqi, Yu, Yuanchao, Wang, Jingjing, He, Lu, Siddiqui, Faiza Amber, Chen, Lumeng, Zhu, Liying, Zhou, Dan, Qin, Junling, Miao, Jun, Cui, Liwang, Cao, Yaming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426563/
https://www.ncbi.nlm.nih.gov/pubmed/35938722
http://dx.doi.org/10.1128/mbio.01897-22

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