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Differential Binding of Carbapenems with the AdeABC Efflux Pump and Modulation of the Expression of AdeB Linked to Novel Mutations within Two-Component System AdeRS in Carbapenem-Resistant Acinetobacter baumannii

Resistance-nodulation-division-type efflux system AdeABC plays an important role in carbapenem resistance among Acinetobacter baumannii. However, a knowledge gap is observed regarding the role of its regulator AdeRS in carbapenem-resistant A. baumannii (CRAB). This study effectively combines microbi...

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Detalles Bibliográficos
Autores principales: Roy, Subhasree, Junghare, Vivek, Dutta, Shanta, Hazra, Saugata, Basu, Sulagna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426577/
https://www.ncbi.nlm.nih.gov/pubmed/35735748
http://dx.doi.org/10.1128/msystems.00217-22