Phosphatidylinositol 3-Kinase (PI3K) Orchestrates Aspergillus fumigatus-Induced Eosinophil Activation Independently of Canonical Toll-Like Receptor (TLR)/C-Type-Lectin Receptor (CLR) Signaling

Eosinophilia is associated with various persisting inflammatory diseases and often coincides with chronic fungal infections or fungal allergy as in the case of allergic bronchopulmonary aspergillosis (ABPA). Here, we show that intranasal administration of live Aspergillus fumigatus conidia causes fa...

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Detalles Bibliográficos
Autores principales: Dietschmann, Axel, Schruefer, Sebastian, Westermann, Stefanie, Henkel, Fiona, Castiglione, Kirstin, Willebrand, Ralf, Adam, Jasmin, Ruland, Jürgen, Lang, Roland, Sheppard, Donald C., Esser-von-Bieren, Julia, Radtke, Daniel, Krappmann, Sven, Voehringer, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426586/
https://www.ncbi.nlm.nih.gov/pubmed/35695427
http://dx.doi.org/10.1128/mbio.01239-22

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