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A Single Dose of Anti-HBsAg Antibody-Encoding mRNA-LNPs Suppressed HBsAg Expression: a Potential Cure of Chronic Hepatitis B Virus Infection

Hepatitis B virus (HBV) infection is a serious global health issue with more than 250 million chronic carriers. It causes liver diseases such as chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma (HCC). Persistent suppression of the HBV surface antigen (HBsAg) is necessary for a functi...

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Detalles Bibliográficos
Autores principales:	Chen, Binfan, Chen, Yuchen, Li, Jian, Wang, Chunyu, Song, Wenping, Wen, Yumei, Lin, Jinzhong, Wu, Yanling, Ying, Tianlei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426588/ https://www.ncbi.nlm.nih.gov/pubmed/35862767 http://dx.doi.org/10.1128/mbio.01612-22

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