Cargando…

Examination of Genome-Wide Ortholog Variation in Clinical and Environmental Isolates of the Fungal Pathogen Aspergillus fumigatus

Aspergillus fumigatus is both an environmental saprobe and an opportunistic human fungal pathogen. Knowledge of genomic variation across A. fumigatus isolates is essential for understanding the evolution of pathogenicity, virulence, and resistance to antifungal drugs. Here, we investigated 206 A. fu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Horta, Maria Augusta C., Steenwyk, Jacob L., Mead, Matthew E., dos Santos, Luciano H. Braz, Zhao, Shu, Gibbons, John G., Marcet-Houben, Marina, Gabaldón, Toni, Rokas, Antonis, Goldman, Gustavo H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426589/ https://www.ncbi.nlm.nih.gov/pubmed/35766381 http://dx.doi.org/10.1128/mbio.01519-22

Ejemplares similares

Extensive Non-Coding Sequence Divergence Between the Major Human Pathogen Aspergillus fumigatus and its Relatives
por: Brown, Alec, et al.
Publicado: (2022)

Evolving moldy murderers: Aspergillus section Fumigati as a model for studying the repeated evolution of fungal pathogenicity
por: Rokas, Antonis, et al.
Publicado: (2020)

Genomic and Phenotypic Heterogeneity of Clinical Isolates of the Human Pathogens Aspergillus fumigatus, Aspergillus lentulus, and Aspergillus fumigatiaffinis
por: dos Santos, Renato A. C., et al.
Publicado: (2020)

Gliotoxin, a Known Virulence Factor in the Major Human Pathogen Aspergillus fumigatus, Is Also Biosynthesized by Its Nonpathogenic Relative Aspergillus fischeri
por: Knowles, Sonja L., et al.
Publicado: (2020)

Characterizing the Pathogenic, Genomic, and Chemical Traits of Aspergillus fischeri, a Close Relative of the Major Human Fungal Pathogen Aspergillus fumigatus
por: Mead, Matthew E., et al.
Publicado: (2019)

Know the enemy and know yourself: Addressing cryptic fungal pathogens of humans and beyond
por: Steenwyk, Jacob L., et al.
Publicado: (2023)

Fungal Isocyanide Synthases and Xanthocillin Biosynthesis in Aspergillus fumigatus
por: Lim, Fang Yun, et al.
Publicado: (2018)

Functional Characterization of Clinical Isolates of the Opportunistic Fungal Pathogen Aspergillus nidulans
por: Bastos, Rafael Wesley, et al.
Publicado: (2020)

A phylogenetic approach to explore the Aspergillus fumigatus conidial surface-associated proteome and its role in pathogenesis
por: Goldman, Gustavo, et al.
Publicado: (2023)

Chromatin profiling reveals heterogeneity in clinical isolates of the human pathogen Aspergillus fumigatus
por: Colabardini, Ana Cristina, et al.
Publicado: (2022)

Examining Signatures of Natural Selection in Antifungal Resistance Genes Across Aspergillus Fungi
por: dos Santos, Renato Augusto Corrêa, et al.
Publicado: (2021)

Genomic and phenotypic analysis of COVID-19-associated pulmonary aspergillosis isolates of Aspergillus fumigatus
por: Steenwyk, Jacob L., et al.
Publicado: (2020)

Genomic and Phenotypic Analysis of COVID-19-Associated Pulmonary Aspergillosis Isolates of Aspergillus fumigatus
por: Steenwyk, Jacob L., et al.
Publicado: (2021)

A Robust Phylogenomic Time Tree for Biotechnologically and Medically Important Fungi in the Genera Aspergillus and Penicillium
por: Steenwyk, Jacob L., et al.
Publicado: (2019)

Draft Genome Sequences of Four Aspergillus Section Fumigati Clinical Strains
por: dos Santos, Renato Augusto Corrêa, et al.
Publicado: (2020)

Aspergillus fumigatus Acetate Utilization Impacts Virulence Traits and Pathogenicity
por: Ries, Laure Nicolas Annick, et al.
Publicado: (2021)

The Tree versus the Forest: The Fungal Tree of Life and the Topological Diversity within the Yeast Phylome
por: Marcet-Houben, Marina, et al.
Publicado: (2009)

Genetic Interactions Between Aspergillus fumigatus Basic Leucine Zipper (bZIP) Transcription Factors AtfA, AtfB, AtfC, and AtfD
por: Silva, Lilian Pereira, et al.
Publicado: (2021)

Nutritional Heterogeneity Among Aspergillus fumigatus Strains Has Consequences for Virulence in a Strain- and Host-Dependent Manner
por: Ries, Laure Nicolas Annick, et al.
Publicado: (2019)

Investigation of Aspergillus fumigatus biofilm formation by various “omics” approaches
por: Muszkieta, Laetitia, et al.
Publicado: (2013)

The Caspofungin Paradoxical Effect is a Tolerant “Eagle Effect” in the Filamentous Fungal Pathogen Aspergillus fumigatus
por: Valero, Clara, et al.
Publicado: (2022)

Phosphoproteomics of Aspergillus fumigatus Exposed to the Antifungal Drug Caspofungin
por: Mattos, Eliciane Cevolani, et al.
Publicado: (2020)

Functional Characterization of an Aspergillus fumigatus Calcium Transporter (PmcA) that Is Essential for Fungal Infection
por: Dinamarco, Taísa Magnani, et al.
Publicado: (2012)

The evolution of the gliotoxin biosynthetic gene cluster in Penicillium fungi
por: Balamurugan, Charu, et al.
Publicado: (2023)

The Aspergillus fumigatus Mismatch Repair MSH2 Homolog Is Important for Virulence and Azole Resistance
por: dos Reis, Thaila Fernanda, et al.
Publicado: (2019)

Regulation of gliotoxin biosynthesis and protection in Aspergillus species
por: de Castro, Patrícia Alves, et al.
Publicado: (2022)

Correction: Functional Characterization of an Aspergillus fumigatus Calcium Transporter (PmcA) that Is Essential for Fungal Infection
por: Dinamarco, Taísa Magnani, et al.
Publicado: (2012)

The Aspergillus fumigatus transcription factor RglT is important for gliotoxin biosynthesis and self-protection, and virulence
por: Ries, Laure N. A., et al.
Publicado: (2020)

Examination of Gene Loss in the DNA Mismatch Repair Pathway and Its Mutational Consequences in a Fungal Phylum
por: Phillips, Megan A, et al.
Publicado: (2021)

SAKrificing an Essential Stress-Sensing Pathway Improves Aspergillus fumigatus Germination
por: Hérivaux, Anaïs, et al.
Publicado: (2022)

A population genomic characterization of copy number variation in the opportunistic fungal pathogen Aspergillus fumigatus
por: Zhao, Shu, et al.
Publicado: (2018)

Identification of possible targets of the Aspergillus fumigatus CRZ1 homologue, CrzA
por: Soriani, Frederico M, et al.
Publicado: (2010)

Fungal siderophore metabolism with a focus on Aspergillus fumigatus
por: Haas, Hubertus
Publicado: (2014)

Examining the Evolution of the Regulatory Circuit Controlling Secondary Metabolism and Development in the Fungal Genus Aspergillus
por: Lind, Abigail L., et al.
Publicado: (2015)

PhylomeDB v3.0: an expanding repository of genome-wide collections of trees, alignments and phylogeny-based orthology and paralogy predictions
por: Huerta-Cepas, Jaime, et al.
Publicado: (2011)

The Fumagillin Gene Cluster, an Example of Hundreds of Genes under veA Control in Aspergillus fumigatus
por: Dhingra, Sourabh, et al.
Publicado: (2013)

OrthoSNAP: A tree splitting and pruning algorithm for retrieving single-copy orthologs from gene family trees
por: Steenwyk, Jacob L., et al.
Publicado: (2022)

Quest for Orthologs Entails Quest for Tree of Life: In Search of the Gene Stream
por: Boeckmann, Brigitte, et al.
Publicado: (2015)

Role of Hydrophobins in Aspergillus fumigatus
por: Valsecchi, Isabel, et al.
Publicado: (2017)

Genomic and Molecular Identification of Genes Contributing to the Caspofungin Paradoxical Effect in Aspergillus fumigatus
por: Zhao, Shu, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_mts2b098uq0rjd7epg1bml6226