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Membrane Protein OTOF Is a Type I Interferon-Induced Entry Inhibitor of HIV-1 in Macrophages

In humans, HIV-1 infection induces innate immune responses mediated mainly by type I interferon (IFN). Type I IFN restricts HIV-1 replication by upregulating the expression of IFN-stimulated genes with diverse anti-HIV properties. In this study, we report that the cell membrane protein otoferlin (OT...

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Detalles Bibliográficos
Autores principales:	Ding, Haibo, Zhang, Xiaowei, Zhu, Zheming, Wang, Shumei, Xiong, Ying, Shang, Hong, Liang, Guoxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426595/ https://www.ncbi.nlm.nih.gov/pubmed/35862790 http://dx.doi.org/10.1128/mbio.01738-22

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