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Symbionts on the Brain: How Wolbachia Is Strictly Corralled in Some Neotropical Drosophila spp.

Wolbachia is a heritable alphaproteobacterial symbiont of arthropods and nematodes, famous for its repertoire of host manipulations, including cytoplasmic incompatibility. To be vertically transmitted, Wolbachia must efficiently colonize the female germ line, although somatic tissues outside the gon...

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Autores principales: Voronin, Denis, Makepeace, Benjamin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426604/
https://www.ncbi.nlm.nih.gov/pubmed/35862784
http://dx.doi.org/10.1128/mbio.01182-22
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author Voronin, Denis
Makepeace, Benjamin L.
author_facet Voronin, Denis
Makepeace, Benjamin L.
author_sort Voronin, Denis
collection PubMed
description Wolbachia is a heritable alphaproteobacterial symbiont of arthropods and nematodes, famous for its repertoire of host manipulations, including cytoplasmic incompatibility. To be vertically transmitted, Wolbachia must efficiently colonize the female germ line, although somatic tissues outside the gonads are also infected. In Drosophila spp., Wolbachia is usually distributed systemically in multiple regions of the adult fly, but in some neotropical hosts, Wolbachia’s only somatic niches are cerebral bacteriocyte-like structures and the ovarian follicle cells. In their recent article, Strunov and colleagues (A. Strunov, K. Schmidt, M. Kapun, and W. J. Miller. mBio 13:e03863-21, 2022, https://doi.org/10.1128/mbio.03863-21) compared the development of Drosophila spp. with systemic or restricted infections and demonstrated that the restricted pattern is determined in early embryogenesis by an apparently novel autophagic process, involving intimate interactions of Wolbachia with the endoplasmic reticulum. This work has implications not only for the evolution of neotropical Drosophila spp. but also for our understanding of how Wolbachia infections are controlled in other native or artificial hosts.
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spelling pubmed-94266042022-08-31 Symbionts on the Brain: How Wolbachia Is Strictly Corralled in Some Neotropical Drosophila spp. Voronin, Denis Makepeace, Benjamin L. mBio Commentary Wolbachia is a heritable alphaproteobacterial symbiont of arthropods and nematodes, famous for its repertoire of host manipulations, including cytoplasmic incompatibility. To be vertically transmitted, Wolbachia must efficiently colonize the female germ line, although somatic tissues outside the gonads are also infected. In Drosophila spp., Wolbachia is usually distributed systemically in multiple regions of the adult fly, but in some neotropical hosts, Wolbachia’s only somatic niches are cerebral bacteriocyte-like structures and the ovarian follicle cells. In their recent article, Strunov and colleagues (A. Strunov, K. Schmidt, M. Kapun, and W. J. Miller. mBio 13:e03863-21, 2022, https://doi.org/10.1128/mbio.03863-21) compared the development of Drosophila spp. with systemic or restricted infections and demonstrated that the restricted pattern is determined in early embryogenesis by an apparently novel autophagic process, involving intimate interactions of Wolbachia with the endoplasmic reticulum. This work has implications not only for the evolution of neotropical Drosophila spp. but also for our understanding of how Wolbachia infections are controlled in other native or artificial hosts. American Society for Microbiology 2022-07-14 /pmc/articles/PMC9426604/ /pubmed/35862784 http://dx.doi.org/10.1128/mbio.01182-22 Text en Copyright © 2022 Voronin and Makepeace. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Commentary
Voronin, Denis
Makepeace, Benjamin L.
Symbionts on the Brain: How Wolbachia Is Strictly Corralled in Some Neotropical Drosophila spp.
title Symbionts on the Brain: How Wolbachia Is Strictly Corralled in Some Neotropical Drosophila spp.
title_full Symbionts on the Brain: How Wolbachia Is Strictly Corralled in Some Neotropical Drosophila spp.
title_fullStr Symbionts on the Brain: How Wolbachia Is Strictly Corralled in Some Neotropical Drosophila spp.
title_full_unstemmed Symbionts on the Brain: How Wolbachia Is Strictly Corralled in Some Neotropical Drosophila spp.
title_short Symbionts on the Brain: How Wolbachia Is Strictly Corralled in Some Neotropical Drosophila spp.
title_sort symbionts on the brain: how wolbachia is strictly corralled in some neotropical drosophila spp.
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426604/
https://www.ncbi.nlm.nih.gov/pubmed/35862784
http://dx.doi.org/10.1128/mbio.01182-22
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