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Ubiquitination of SARS-CoV-2 NSP6 and ORF7a Facilitates NF-κB Activation

Patients with severe coronavirus disease 2019 tend to have high levels of proinflammatory cytokines, which eventually lead to cytokine storm and the development of acute respiratory distress syndrome. However, the detailed molecular mechanisms of proinflammatory cytokine production remain unknown. H...

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Detalles Bibliográficos
Autores principales:	Nishitsuji, Hironori, Iwahori, Satoko, Ohmori, Mariko, Shimotohno, Kunitada, Murata, Takayuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426613/ https://www.ncbi.nlm.nih.gov/pubmed/35856559 http://dx.doi.org/10.1128/mbio.00971-22

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