Characterisation of the Circulating Transcriptomic Landscape in Inflammatory Bowel Disease Provides Evidence for Dysregulation of Multiple Transcription Factors Including NFE2, SPI1, CEBPB, and IRF2

AIM: To assess the pathobiological and translational importance of whole-blood transcriptomic analysis in inflammatory bowel disease [IBD]. METHODS: We analysed whole-blood expression profiles from paired-end sequencing in a discovery cohort of 590 Europeans recruited across six countries in the IBD...

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Detalles Bibliográficos
Autores principales: Nowak, Jan K, Adams, Alex T, Kalla, Rahul, Lindstrøm, Jonas C, Vatn, Simen, Bergemalm, Daniel, Keita, Åsa V, Gomollón, Fernando, Jahnsen, Jørgen, Vatn, Morten H, Ricanek, Petr, Ostrowski, Jerzy, Walkowiak, Jaroslaw, Halfvarson, Jonas, Satsangi, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426667/
https://www.ncbi.nlm.nih.gov/pubmed/35212366
http://dx.doi.org/10.1093/ecco-jcc/jjac033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426667/
https://www.ncbi.nlm.nih.gov/pubmed/35212366
http://dx.doi.org/10.1093/ecco-jcc/jjac033

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