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Characterisation of the Circulating Transcriptomic Landscape in Inflammatory Bowel Disease Provides Evidence for Dysregulation of Multiple Transcription Factors Including NFE2, SPI1, CEBPB, and IRF2
AIM: To assess the pathobiological and translational importance of whole-blood transcriptomic analysis in inflammatory bowel disease [IBD]. METHODS: We analysed whole-blood expression profiles from paired-end sequencing in a discovery cohort of 590 Europeans recruited across six countries in the IBD...
Autores principales: | Nowak, Jan K, Adams, Alex T, Kalla, Rahul, Lindstrøm, Jonas C, Vatn, Simen, Bergemalm, Daniel, Keita, Åsa V, Gomollón, Fernando, Jahnsen, Jørgen, Vatn, Morten H, Ricanek, Petr, Ostrowski, Jerzy, Walkowiak, Jaroslaw, Halfvarson, Jonas, Satsangi, Jack |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426667/ https://www.ncbi.nlm.nih.gov/pubmed/35212366 http://dx.doi.org/10.1093/ecco-jcc/jjac033 |
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