Morinda officinalis oligosaccharides mitigate chronic mild stress-induced inflammation and depression-like behaviour by deactivating the MyD88/PI3K pathway via E2F2

Morinda officinalis oligosaccharides (MOs) are natural herbal extracts that have been shown to exert antidepressant effects. However, the mechanism of this effect remains unclear. Here, we explored the mechanism by which MOs improved experimental depression. Using a chronic mild stress (CMS) murine...

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Detalles Bibliográficos
Autores principales: Zhu, Zhen-Hua, Yin, Xu-Yuan, Xu, Tu-Sun, Tao, Wei-Wei, Yao, Guang-Da, Wang, Pei-Jie, Qi, Qi, Jia, Qiu-Fang, Wang, Jing, Zhu, Yue, Hui, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426723/
https://www.ncbi.nlm.nih.gov/pubmed/36052143
http://dx.doi.org/10.3389/fphar.2022.855964

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