Cargando…

Efficacy, Safety, and Tolerability of Centanafadine Sustained-Release Tablets in Adults With Attention-Deficit/Hyperactivity Disorder: Results of 2 Phase 3, Randomized, Double-blind, Multicenter, Placebo-Controlled Trials

PURPOSE/BACKGROUND: Centanafadine is an inhibitor of norepinephrine, dopamine, and serotonin reuptake transporters under investigation for the treatment of attention-deficit/hyperactivity disorder (ADHD). METHODS/PROCEDURES: Two phase 3 randomized, double-blind, placebo-controlled, parallel-group st...

Descripción completa

Detalles Bibliográficos
Autores principales:	Adler, Lenard A., Adams, Julie, Madera-McDonough, Jessica, Kohegyi, Eva, Hobart, Mary, Chang, Denise, Angelicola, Mark, McQuade, Robert, Liebowitz, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2022
Materias:	Original Contributions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426730/ https://www.ncbi.nlm.nih.gov/pubmed/35652746 http://dx.doi.org/10.1097/JCP.0000000000001575

Ejemplares similares

Safety and Efficacy of Centanafadine Sustained-Release in Adults With Attention-Deficit Hyperactivity Disorder: Results of Phase 2 Studies
por: Wigal, Sharon B, et al.
Publicado: (2020)

Efficacy of atomoxetine in adult attention-Deficit/Hyperactivity Disorder: a drug-placebo response curve analysis
por: Faraone, Stephen V, et al.
Publicado: (2005)

Maternal serum Vitamin B12 and offspring attention-deficit/hyperactivity disorder (ADHD)
por: Sourander, Andre, et al.
Publicado: (2020)

A Long-Term, Open-Label Study to Evaluate the Safety and Tolerability of Brexpiprazole as Adjunctive Therapy in Adults With Major Depressive Disorder
por: Hobart, Mary, et al.
Publicado: (2019)

A Phase 3, Placebo-Controlled Trial of Once-Daily Viloxazine Extended-Release Capsules in Adolescents With Attention-Deficit/Hyperactivity Disorder
por: Nasser, Azmi, et al.
Publicado: (2021)

Effect of lisdexamfetamine dimesylate on sleep in adults with attention-deficit/hyperactivity disorder
por: Adler, Lenard A, et al.
Publicado: (2009)

Continuity in features of anxiety and attention deficit/hyperactivity disorder in young preschool children
por: Overgaard, Kristin Romvig, et al.
Publicado: (2014)

Risk factors for comorbid oppositional defiant disorder in attention-deficit/hyperactivity disorder
por: Noordermeer, Siri D. S., et al.
Publicado: (2017)

Atomoxetine improves patient and family coping in attention deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled study in Swedish children and adolescents
por: Svanborg, Pär, et al.
Publicado: (2009)

Predictive validity of attention-deficit/hyperactivity disorder from ages 3 to 5 Years
por: Overgaard, Kristin Romvig, et al.
Publicado: (2021)

Neurotransmitter transporter occupancy following administration of centanafadine sustained-release tablets: A phase 1 study in healthy male adults
por: Matuskey, David, et al.
Publicado: (2022)

The influence of comorbid oppositional defiant disorder on white matter microstructure in attention-deficit/hyperactivity disorder
por: van Ewijk, Hanneke, et al.
Publicado: (2015)

Maternal serum C-reactive protein (CRP) and offspring attention deficit hyperactivity disorder (ADHD)
por: Chudal, Roshan, et al.
Publicado: (2019)

Suggestive diagnosis of attention-deficit/hyperactivity disorder in indigenous children and adolescents from the Brazilian Amazon
por: e Azevêdo, Paulo Verlaine Borges, et al.
Publicado: (2019)

Sleep, chronotype, and sleep hygiene in children with attention-deficit/hyperactivity disorder, autism spectrum disorder, and controls
por: van der Heijden, K. B., et al.
Publicado: (2017)

Beliefs regarding medication and side effects influence treatment adherence in adolescents with attention deficit hyperactivity disorder
por: Emilsson, Maria, et al.
Publicado: (2016)

Maternal personality traits moderate treatment response in the Multimodal Treatment Study of attention-deficit/hyperactivity disorder
por: Perez Algorta, Guillermo, et al.
Publicado: (2019)

Differential utility of teacher and parent–teacher combined information in the assessment of Attention Deficit/Hyperactivity Disorder symptoms
por: Garcia-Rosales, Alexandra, et al.
Publicado: (2020)

Attention-deficit/hyperactivity disorder from preschool to school age: change and stability of parent and teacher reports
por: Overgaard, Kristin Romvig, et al.
Publicado: (2022)

Health-related quality of life of children with attention-deficit/hyperactivity disorder versus children with diabetes and healthy controls
por: Coghill, David, et al.
Publicado: (2015)

Stimulant treatment profiles predicting co-occurring substance use disorders in individuals with attention-deficit/hyperactivity disorder
por: Groenman, Annabeth P., et al.
Publicado: (2019)

Gestational Exposure to Organophosphate Pesticides and Longitudinally Assessed Behaviors Related to Attention-Deficit/Hyperactivity Disorder and Executive Function
por: Sagiv, Sharon K, et al.
Publicado: (2021)

The Effect of Attention Deficit/Hyperactivity Disorder on Physical Health Outcomes: A 2-Sample Mendelian Randomization Study
por: Leppert, Beate, et al.
Publicado: (2020)

Amygdala reactivity and ventromedial prefrontal cortex coupling in the processing of emotional face stimuli in attention-deficit/hyperactivity disorder
por: Viering, Tammo, et al.
Publicado: (2021)

Baseline characteristics of European and non-European adult patients with attention deficit hyperactivity disorder participating in a placebo-controlled, randomized treatment study with atomoxetine
por: Upadhyaya, Himanshu, et al.
Publicado: (2013)

A mendelian randomization study on causal effects of 25(OH)vitamin D levels on attention deficit/hyperactivity disorder
por: Libuda, Lars, et al.
Publicado: (2020)

Which factors determine clinicians’ policy and attitudes towards medication and parent training for children with Attention-Deficit/Hyperactivity Disorder?
por: Dekkers, Tycho J., et al.
Publicado: (2021)

Evaluation of a structured skills training group for adolescents with attention-deficit/hyperactivity disorder: a randomised controlled trial
por: Meyer, Jenny, et al.
Publicado: (2021)

Age at school entry and reported symptoms of attention-deficit/hyperactivity in first graders: results of the prospective cohort study ikidS
por: Diefenbach, Christiane, et al.
Publicado: (2021)

Serum matrix metalloproteinase-9 levels and severity of symptoms in boys with attention deficit hyperactivity disorder ADHD/hyperkinetic disorder HKD
por: Kadziela-Olech, Halina, et al.
Publicado: (2014)

Associations between attention-deficit/hyperactivity disorder and autoimmune diseases are modified by sex: a population-based cross-sectional study
por: Hegvik, Tor-Arne, et al.
Publicado: (2017)

Resumption of attention-deficit hyperactivity disorder medication in early adulthood: findings from a UK primary care prescribing study
por: Newlove-Delgado, Tamsin, et al.
Publicado: (2019)

A randomized controlled study of remote computerized cognitive, neurofeedback, and combined training in the treatment of children with attention-deficit/hyperactivity disorder
por: Luo, Xiangsheng, et al.
Publicado: (2022)

Efficacy of lisdexamfetamine dimesylate throughout the day in children and adolescents with attention-deficit/hyperactivity disorder: results from a randomized, controlled trial
por: Coghill, David R., et al.
Publicado: (2013)

Autism spectrum disorder and attention-deficit/hyperactivity disorder in children with cerebral palsy: results from screening in a population-based group
por: Påhlman, Magnus, et al.
Publicado: (2020)

The temporal order of fluctuations in atopic disease symptoms and attention-deficit/hyperactivity disorder symptoms: a time-series study in ADHD patients
por: van der Schans, Jurjen, et al.
Publicado: (2019)

Validation of the adult attention-deficit/hyperactivity disorder quality-of-life scale in European patients: comparison with patients from the USA
por: Brod, Meryl, et al.
Publicado: (2015)

A review of modafinil film-coated tablets for attention-deficit/hyperactivity disorder in children and adolescents
por: Rugino, Thomas
Publicado: (2007)

Randomized, Double-Blind, Placebo-Controlled Trial Demonstrates the Efficacy and Safety of Oral Aripiprazole for the Treatment of Tourette's Disorder in Children and Adolescents
por: Sallee, Floyd, et al.
Publicado: (2017)

Self-Reported quality of life in adults with attention-deficit/hyperactivity disorder and executive function impairment treated with lisdexamfetamine dimesylate: a randomized, double-blind, multicenter, placebo-controlled, parallel-group study
por: Adler, Lenard A, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_vs4raujkuv6n43hmlte7gctokk