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Antinociceptive and Analgesic Effects of (2R,6R)-Hydroxynorketamine

Commonly used pain therapeutics, such as opioid medications, exert dangerous side effects and lack effectiveness in treating some types of pain. Ketamine is also used to treat pain, but side effects limit its widespread use. (2R,6R)-hydroxynorketamine (HNK) is a ketamine metabolite that potentially...

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Detalles Bibliográficos
Autores principales:	Yost, Jonathan G., Wulf, Hildegard A., Browne, Caroline A., Lucki, Irwin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Pharmacology and Experimental Therapeutics 2022
Materias:	Behavioral Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426759/ https://www.ncbi.nlm.nih.gov/pubmed/35779947 http://dx.doi.org/10.1124/jpet.122.001278

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