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Scelestial: Fast and accurate single-cell lineage tree inference based on a Steiner tree approximation algorithm

Single-cell genome sequencing provides a highly granular view of biological systems but is affected by high error rates, allelic amplification bias, and uneven genome coverage. This creates a need for data-specific computational methods, for purposes such as for cell lineage tree inference. The obje...

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Detalles Bibliográficos
Autores principales: Foroughmand-Araabi, Mohammad-Hadi, Goliaei, Sama, McHardy, Alice C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426887/
https://www.ncbi.nlm.nih.gov/pubmed/35951662
http://dx.doi.org/10.1371/journal.pcbi.1009100