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Scelestial: Fast and accurate single-cell lineage tree inference based on a Steiner tree approximation algorithm
Single-cell genome sequencing provides a highly granular view of biological systems but is affected by high error rates, allelic amplification bias, and uneven genome coverage. This creates a need for data-specific computational methods, for purposes such as for cell lineage tree inference. The obje...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426887/ https://www.ncbi.nlm.nih.gov/pubmed/35951662 http://dx.doi.org/10.1371/journal.pcbi.1009100 |